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KMID : 0359720220400020181
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Journal of the Korean Neurological Association
2022 Volume.40 No. 2 p.181 ~ p.184
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A Diagnostic Dilemma: Normal Repetitive Nerve Stimulation in Lambert-Eaton Myasthenic Syndrome
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Jeong Yu-Hun
Seok Hung-Youl
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Abstract
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It is important for the diagnosis of Lambert-Eaton myasthenic syndrome (LEMS) to confirm the incremental response at high-rate stimulation or after brief exercise in the repetitive nerve stimulation (RNS) test. Therefore, it may be difficult to diagnose LEMS if the RNS test is normal initially. We report a patient with LEMS whose diagnosis was delayed due to normal RNS findings. We believe that anti-P/Q-type voltage-gated calcium channel antibody testing is crucial in the diagnosis of LEMS.
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KEYWORD
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Lambert-Eaton myasthenic syndrome, Electrodiagnosis, Anti-voltage-gated calcium channel autoantibody
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